反应详情

A mixture of 15 g of decylamine, 5.48 g of gamma butyrolactone, 100 ml of toluene, and 20 mg of zinc chloride was refluxed under nitrogen for 4 days. Upon cooling the reaction mixture formed a precipitate which was recrystallized from toluene to yield 6.91 g (44.6%) of N-decyl-4-hydroxybutyramide, m.p. 74-75° C.

1. temperaturewas refluxed under nitrogen for 4 days
2. temperatureUpon cooling the reaction mixture
3. customformed a precipitate which
4. customwas recrystallized from toluene