Hydrazine hydrate (1:1) → HCID 178428720, compound

HRID 477554Notes

Reaction equation

HRID 477554 reaction equation
[OH:1][C:2]1[N:7]=[C:6](S)[CH:5]=[C:4]([CH3:9])[N:3]=1.O.[NH2:11][NH2:12]>C(O)C>[NH:11]([C:6]1[CH:5]=[C:4]([CH3:9])[N:3]=[C:2]([OH:1])[N:7]=1)[NH2:12]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 178429729HCID 178429729, compound

Product 1

HCID 178428720HCID 178428720, compoundYield 87.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product obtained in Step 1 (3.0 g) was suspended in 30 ml of ethanol at room temperature. Hydrazine monohydrate (3.17 g) was added dropwise to this suspension and the mixture was refluxed for two hours. After cooling to room temperature, the formed crystals were collected by filtration and washed with 20 ml of ethanol, giving 2.6 g of the objective compound as red crystals.

Workup

  1. temperaturethe mixture was refluxed for two hours
  2. filtrationthe formed crystals were collected by filtration
  3. washwashed with 20 ml of ethanol

Sources & evidence

ORD record
ord-8c4b39623a354dbbbde3a2218fde25ea
Source dataset
uspto-grants-1989_12
Patent number
US04888332

Reaction notes

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