Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Urea | HCID 1176 | — |
| Reactant | 6-chloro-N4-methylpyrimidine-4,5-diamine | HCID 308477 | — |
| Product | HCID 178481592 | HCID 178481592 | 60% |
Reaction Steps
A mixture of 4.76 parts of 6-chloro-N4 methyl-4,5-pyrimidinediamine and 7.2 parts of urea was stirred and heated for 1 hour at 180° C. After cooling, the residue was suspended in water. The product was filtered off and dried, yielding 3.3 parts (60%) of 6-chloro-9-methyl-9H-purin-8-ol (intermediate 174).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04888426 |
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| Source dataset | uspto-grants-1989_12 |
|---|
| ORD ID | ord-9db95f73ebdf482c836e96b5273446f7 |
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| Source note | uspto-grants-1989_12 |
|---|
