Hydrochloric Acid → HCID 178509071, compound

HRID 477742Notes

Reaction equation

HRID 477742 reaction equation
[NH+]1C=CC=CC=1.C([N:10]1[C:14]([NH2:15])=[N:13][C:12]([S:16]([NH:19][C:20]2[C:25]([Cl:26])=[CH:24][CH:23]=[CH:22][C:21]=2[Cl:27])(=[O:18])=[O:17])=[N:11]1)(=O)C.Cl>[OH-].[Na+]>[Cl:26][C:25]1[CH:24]=[CH:23][CH:22]=[C:21]([Cl:27])[C:20]=1[NH:19][S:16]([C:12]1[N:13]=[C:14]([NH2:15])[NH:10][N:11]=1)(=[O:18])=[O:17]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19872285HCID 19872285, compound

Product 1

HCID 178509071HCID 178509071, compoundYield 92.2%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The product of stage (d) (53.6 g) was dissolved in 2N sodium hydroxide (200 ml), and was stirred at room temperature for 10 minutes. The solution was then taken to pH=5 with 2N hydrochloric acid, and the product was filtered off, washed with a little water and ether, and then dried in vacuo to give 35.4 g of the desired product, mp 265°-267° C.

Workup

  1. filtrationthe product was filtered off
  2. washwashed with a little water and ether
  3. customdried in vacuo

Sources & evidence

ORD record
ord-cad8fd92a7b4436fa56e58b7fe6dae7a
Source dataset
uspto-grants-1989_12
Patent number
US04889553

Reaction notes

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