Piperidine → HCID 14652588, compound

HRID 477818Notes

Reaction equation

HRID 477818 reaction equation
[Cl:1][CH2:2][CH:3]1[O:8][CH2:7][CH2:6][N:5](CC2C=CC=CC=2)[CH2:4]1.[NH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[ClH:1].[ClH:1].[N:16]1([CH2:2][CH:3]2[O:8][CH2:7][CH2:6][NH:5][CH2:4]2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 28015624-Benzyl-2-(chloromethyl)morpholine

Product 1

HCID 14652588HCID 14652588, compound

Procedure

By the use of 2-chloromethyl-4-benzylmorpholine and piperidine, the reaction is similarly carried out as Reference example 2 to give 2-(piperidinomethyl)morpholine dihydrochloride as white crystals, melting at 172°-174° C. with decomposition.

Sources & evidence

ORD record
ord-0f08749e8a1c42b891410bd0b2adea4e
Source dataset
uspto-grants-1989_12
Patent number
US04889857

Reaction notes

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