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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477853Generated: November 1, 2026

1-(2,4-Difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → 1-(2,4-Difluorophenyl)-6,8-difluoro-1,4-dihydro-7-[2-(2-methylaminoethyl)morpholino]-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/477853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4-Difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 14476011—
ReactantHCID 14652595HCID 14652595—
Product1-(2,4-Difluorophenyl)-6,8-difluoro-1,4-dihydro-7-[2-(2-methylaminoethyl)morpholino]-4-oxoquinoline-3-carboxylic acidHCID 19834956—

Reaction Steps

By the use of 1-(2,4-difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 2-(2 -methylaminoethyl)morpholine, the reaction is similarly carried but as Example 26 to give 1-(2,4-difluorophenyl)-6,8-difluoro-1,4-dihydro-7-[2-(2-methylaminoethyl)morpholino]-4-oxoquinoline-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04889857
Source datasetuspto-grants-1989_12
ORD IDord-800d5f9ed24b4549a7dde4abf7b491a8
Source noteuspto-grants-1989_12