1,2,3,4-Tetrahydro-2-naphthalenol → 4a-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone
反応式
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[OH:11].[CH3:12]C(C)=O.OS(O)(=O)=O.O=[Cr](=O)=O>>[CH3:12][C:5]12[CH2:6][CH2:7][CH:8]=[CH:9][C:10]1=[CH:1][C:2](=[O:11])[CH2:3][CH2:4]2参加物
3
実験手順
1,2,3,4-Tetrahydro-2-napthol is reduced according to Preparation 9. The resulting diene is cyclopropanated with Simmons-Smith reagent, oxidized with Jones reagent, then the cyclopropane ring opened with acid to form dienone 4.
出典と根拠
- ORDレコード
- ord-5fcac40704fb4370b939c22b0213d194
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04889947
反応ノート
読み込み中…