化工社化工社 化学情報印刷レポート · 研究参考用
1,2,3,4-Tetrahydro-2-naphthalenol → 4a-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,4-Tetrahydro-2-naphthalenol | HCID 10747 | — |
| 反応物 | Jones' reagent | HCID 131709961 | — |
| 生成物 | 4a-Methyl-4,4a,5,6-tetrahydro-2(3H)-naphthalenone | HCID 277447 | — |
反応手順
1,2,3,4-Tetrahydro-2-napthol is reduced according to Preparation 9. The resulting diene is cyclopropanated with Simmons-Smith reagent, oxidized with Jones reagent, then the cyclopropane ring opened with acid to form dienone 4.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04889947 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-5fcac40704fb4370b939c22b0213d194 |
| 出典メモ | uspto-grants-1989_12 |