HuagongsheHuagongshe Chemistry Print Report · For research reference only
Batyl Alcohol → 1-O-Octadecyl-3-O-[2-[2-(2-trityloxyethoxy)ethoxy]ethyl]glycerol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Batyl Alcohol | HCID 3681 | — |
| Reactant | Trityl chloride | HCID 6456 | — |
| Reactant | Triethylene Glycol | HCID 8172 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Sodium 4-methylbenzenesulfonate | HCID 3720192 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-O-Octadecyl-3-O-[2-[2-(2-trityloxyethoxy)ethoxy]ethyl]glycerol | HCID 14877714 | 42.2% |
Reaction Steps
10.3 g (30 millimole) of batyl alcohol, 6.1 g (32 millimole) of sodium p-toluenesulfonate, 50 ml of pyridine, 1.6 g (40 millimole) of 60% oily sodium hydride, 45 g (300 millimole) of triethylene glycol, and 8.4 g (30 millimole) of trityl chloride were treated by following a procedure similar to that of Working Example 1, to give 9.1 g (42%) of the above-captioned compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04889953 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-86ee1e5ae9874216bdc3b8f1993af70d |
| Source note | uspto-grants-1989_12 |