HRID478093

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3681

3-(Octadecyloxy)-1,2-propanediol

C21H44O3

HCID6456

Trityl chloride

C19H15Cl

HCID8172

Triethylene glycol

C6H14O4

HCID24758

Sodium hydride

HNa

HCID3720192

Sodium 4-methylbenzenesulfonate

C7H7NaO3S

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCOCC(O)COCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1

HCID14877714

未命名化合物

收率 42.2%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

10.3 g (30 millimole) of batyl alcohol, 6.1 g (32 millimole) of sodium p-toluenesulfonate, 50 ml of pyridine, 1.6 g (40 millimole) of 60% oily sodium hydride, 45 g (300 millimole) of triethylene glycol, and 8.4 g (30 millimole) of trityl chloride were treated by following a procedure similar to that of Working Example 1, to give 9.1 g (42%) of the above-captioned compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-86ee1e5ae9874216bdc3b8f1993af70d
来源数据集: uspto-grants-1989_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04889953
来源说明: uspto-grants-1989_12

反应 SMILES

[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][O:19][CH2:20][CH:21]([OH:24])[CH2:22][OH:23].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[Na+].[H-].[Na+].[CH2:39](O)[CH2:40][O:41][CH2:42][CH2:43][O:44][CH2:45][CH2:46][OH:47].[C:49](Cl)([C:62]1[CH:67]=[CH:66][CH:65]=[CH:64][CH:63]=1)([C:56]1[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=1)[C:50]1[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=1>N1C=CC=CC=1>[CH2:18]([O:19][CH2:20][CH:21]([CH2:22][O:23][CH2:39][CH2:40][O:41][CH2:42][CH2:43][O:44][CH2:45][CH2:46][O:47][C:49]([C:62]1[CH:67]=[CH:66][CH:65]=[CH:64][CH:63]=1)([C:56]1[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=1)[C:50]1[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=1)[OH:24])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH3:1]