HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18001201, compound → 6306-59-8
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18001201 | HCID 18001201 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6306-59-8 | HCID 18001258 | 115.7% |
Reaction Steps
To a solution of 1-(3-(N-benzyl-N-methylamino)propyl)piperidine hydrochloride (0.82 g, 2.6 mmol) in methanol (50 mL) was added 5% palladium/carbon (0.16 g), and the mixture was stirred under hydrogen atmosphere at room temperature overnight. After filtrating the reaction mixture through Celite, the filtrate was concentrated to afford the title compound (0.58 g, yield: 99%) as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642228B1 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-de99b76076ba445c9a66437efc6a03b0 |
| Source note | uspto-grants-2003_11 |