Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478200Generated: October 30, 2026

HCID 18001201, compound → 6306-59-8

https://huagongshe.com/reaction/478200

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18001201HCID 18001201—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product6306-59-8HCID 18001258115.7%

Reaction Steps

To a solution of 1-(3-(N-benzyl-N-methylamino)propyl)piperidine hydrochloride (0.82 g, 2.6 mmol) in methanol (50 mL) was added 5% palladium/carbon (0.16 g), and the mixture was stirred under hydrogen atmosphere at room temperature overnight. After filtrating the reaction mixture through Celite, the filtrate was concentrated to afford the title compound (0.58 g, yield: 99%) as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642228B1
Source datasetuspto-grants-2003_11
ORD IDord-de99b76076ba445c9a66437efc6a03b0
Source noteuspto-grants-2003_11