p-Isopropylphenyl isocyanate → 2-Benzyloxy-3-(4-{2-[1-heptyl-3-(4-isopropyl-phenyl)-ureido]-ethyl}-phenyl)-propionic acid ethyl ester

Participants

Reaction Steps

Synthesized from 2-benzyloxy-3-{4-[2-(tert-butoxycarbonyl-heptyl-amino)-ethyl]-phenyl}-propionic acid ethyl ester using procedures analogous to that used for Example 8 immediately followed by Example 10 and substituting 1-isocyanato-4-isopropyl-benzene in the place of 2,4-dimethoxyphenylisocyanate to give crude 2-benzyloxy-3-(4-{2-[1-heptyl-3-(4-isopropyl-phenyl)-ureido]-ethyl}-phenyl)-propionic acid ethyl ester.

Provenance & Evidence