反应详情

温度

110 °C

The product from Example 71A (0.095 g, 0.21 mmol) in chloroform (5 mL) was treated with N-bromosuccinimide (0.037 g, 0.21 mmol) and heated to 110° C. for 16 hours. The mixture was cooled to ambient temperature and purified by chromatography on silica gel eluting with 5% methanol in dichloromethane to provide the title compound (0.043 g).

1. temperatureThe mixture was cooled to ambient temperature
2. custompurified by chromatography on silica gel eluting with 5% methanol in dichloromethane