HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl (1-methyl-2-oxopropoxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl [(1-methyl-2-propynyl)oxy]acetate | HCID 18619750 | — |
| Catalyst | Mercuric acetate | HCID 15337 | — |
| Product | Methyl (1-methyl-2-oxopropoxy)acetate | HCID 71360827 | — |
Reaction Steps
The product from Example 84A (20 g, 0.14 mol) in methanol (700 mL) was treated with mercury(II) acetate (4.6 g, 0.014 mol), heated to reflux for 1 hour, concentrated to approximately 100 mL total volume, treated with 1M HCl (100 mL) and extracted with dichloromethane (3×, 100 mL). The extractions were combined, dried (MgSO4), filtered and concentrated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642222B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-9f1dc2b8afbf41bd9233f749e5179f92 |
| Source note | uspto-grants-2003_11 |