反应详情

The product from Example 84A (20 g, 0.14 mol) in methanol (700 mL) was treated with mercury(II) acetate (4.6 g, 0.014 mol), heated to reflux for 1 hour, concentrated to approximately 100 mL total volume, treated with 1M HCl (100 mL) and extracted with dichloromethane (3×, 100 mL). The extractions were combined, dried (MgSO4), filtered and concentrated to provide the title compound.

1. temperatureheated
2. temperatureto reflux for 1 hour
3. concentrationconcentrated to approximately 100 mL total volume
4. additiontreated with 1M HCl (100 mL)
5. extractionextracted with dichloromethane (3×, 100 mL)
6. extractionThe extractions
7. dry with materialdried (MgSO4)
8. filtrationfiltered
9. concentrationconcentrated