反应详情

The product from Example 84C (3.0 g, 23 mmol) was dissolved in ethanol (50 mL), treated with concentrated sulfuric acid (5 drops), heated to reflux for 3 hours and concentrated. The residue was purified by chromatography eluting with 10:1 and then 5:1 and then 2:1 hexane:ethyl acetate to provide the title compound as the faster moving isomer.

1. temperatureheated
2. temperatureto reflux for 3 hours
3. concentrationconcentrated
4. customThe residue was purified by chromatography
5. washeluting with 10:1