HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 5-ethoxy-2-methyl-2H-pyran-3(6H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-methyl-2H-pyran-3,5(4H,6H)-dione | HCID 23497474 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | 5-ethoxy-2-methyl-2H-pyran-3(6H)-one | HCID 18001005 | — |
Reaction Steps
The product from Example 84C (3.0 g, 23 mmol) was dissolved in ethanol (50 mL), treated with concentrated sulfuric acid (5 drops), heated to reflux for 3 hours and concentrated. The residue was purified by chromatography eluting with 10:1 and then 5:1 and then 2:1 hexane:ethyl acetate to provide the title compound as the faster moving isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642222B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-13a9e2ec99674901be2c87a3f05fe087 |
| Source note | uspto-grants-2003_11 |