Ammonia → HCID 11579171, compound

HRID 478316Notes

Reaction equation

HRID 478316 reaction equation
[CH3:1][CH:2]([CH3:11])[C:3](=O)[CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6].[NH3:12]>C(O)C>[NH2:12]/[C:3](/[CH:2]([CH3:11])[CH3:1])=[CH:4]/[C:5]([O:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 81583Ethyl isobutyrylacetate

Product 1

HCID 11579171HCID 11579171, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 4-methyl-3-oxopentanoate (2.0 g, 13 mmol) was treated with 2M ammonia in ethanol (20 mL), heated to 80 C. in a sealed tube for 16 hours and concentrated to dryness to provide the title compound.

Workup

  1. temperatureheated to 80 C
  2. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-c5e9ed08b4464414a250cd03cf1e8d62
Source dataset
uspto-grants-2003_11
Patent number
US06642222B2

Reaction notes

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