HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → Rac-cis-(3,5-bis-trifluoromethyl-phenyl)-[3-(3,4-dichloro-phenyl)-4-morpholin-4-yl-piperidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzoyl chloride | HCID 101856 | — |
| Reactant | 1-Benzyl-3-(3,4-dichlorophenyl)-4-piperidinone | HCID 18001166 | — |
| Product | Rac-cis-(3,5-bis-trifluoromethyl-phenyl)-[3-(3,4-dichloro-phenyl)-4-morpholin-4-yl-piperidin-1-yl]-methanone | HCID 131724183 | — |
Reaction Steps
The title compound, MS: m/e=555.1 (M+H+), was prepared in accordance with the general method of example 26 from 1-benzyl-3-(3,4-dichloro-phenyl)-piperidin-4-one, morpholine and 3,5-bistrifluoromethyl-benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642226B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-b9951836962443de850a220c15612715 |
| Source note | uspto-grants-2003_11 |