Formaldehyde → HCID 18001173, compound

Participants

Reaction Steps

The title compound, MS: m/e=534.3 (M+H+), [α]58920=−53.04, [α]54620=−65.78, [α]43620=−135.72, [α]36520=−277.94 (c=0.3846, chloroform), was prepared in accordance with the general methods of example 102 (part1) and example 125 from (−)-(1-{4-[1-(3,5-bis-trifluoromethyl-benzoyl)-3-(4-chloro-phenyl)-piperidin-4-yl]-piperazin-1-yl}-2,2,2-trifluoro-ethanone and formaldehyde.

Provenance & Evidence