Cyclopentanol → 2,6-Dichloro-9-cyclopentenylpurine

HRID 478479Notes

Reaction equation

HRID 478479 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4]([Cl:11])[N:3]=1.[C:12]1(O)[CH2:16][CH2:15][CH2:14][CH:13]=1.C1(O)CCCC1>>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[C:12]2[CH2:16][CH2:15][CH2:14][CH:13]=2)=[C:4]([Cl:11])[N:3]=1

Participants

4

Reactant 3

HCID 7298CyclopentanolHCID 18569CyclopentenolHCID 53244122,6-Dichloropurine

Product 1

HCID 180021022,6-Dichloro-9-cyclopentenylpurine

Procedure

2,6-Dichloro-9-cyclopentenylpurine is prepared from 2,6-dichloropurine and cyclopentenol essentially as described in Example 1, Scheme A, step a, but substituting cyclopentenol for cyclopentanol.

Sources & evidence

ORD record
ord-0b46d22833774dd0b2bdf205691a1c0c
Source dataset
uspto-grants-2003_11
Patent number
US06642231B2

Reaction notes

Loading…