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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478482Generated: October 26, 2026

4-Methoxybenzylamine → 2-Chloro-9-isopropyl-N-(4-methoxybenzyl)-9H-purin-6-amine

https://huagongshe.com/reaction/478482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
Reactant2,6-dichloro-9-(propan-2-yl)-9H-purineHCID 11218490—
SolventTriethylamineHCID 8471—
Product2-Chloro-9-isopropyl-N-(4-methoxybenzyl)-9H-purin-6-amineHCID 9858785—

Reaction Steps

2-Chloro-6-[(4-methoxybenzyl)amino]-9-(2-propyl)purine is prepared from 2,6-dichloro-9-(2-propyl)purine (see Example 19 for preparation), 4-methoxybenzylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642231B2
Source datasetuspto-grants-2003_11
ORD IDord-65746d6c97264ccaa71270c983479adc
Source noteuspto-grants-2003_11