Hydroxyamine hydrochloride → 1-(3-Methoxybenzyl)-4-piperidone oxime

HRID 478488Notes

Reaction equation

HRID 478488 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[CH2:6][N:7]1[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]1.Cl.[NH2:18][OH:19]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[CH2:6][N:7]1[CH2:12][CH2:11][C:10](=[N:18][OH:19])[CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 119595401-[(3-Methoxyphenyl)methyl]piperidin-4-one

Product 1

HCID 126418271-(3-Methoxybenzyl)-4-piperidone oxime

Procedure

1-(3-Methoxybenzyl)-4-piperidone oxime is prepared from 1-(3-methoxybenzyl)-4-piperidone and hydroxylamine hydrochloride essentially as described above in Example 38, Scheme C, step b.

Sources & evidence

ORD record
ord-2ee1daebc8b2469dad569802293729d1
Source dataset
uspto-grants-2003_11
Patent number
US06642231B2

Reaction notes

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