m,alpha-Dichlorotoluene → HCID 10489300, compound

HRID 478489Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.[Cl:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12]Cl>>[Cl:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 12103m,alpha-Dichlorotoluene

HCID 337214-Piperidone

Product 1

HCID 10489300HCID 10489300, compound

Procedure

1-(3-Chlorobenzyl)-4-piperidone is prepared from 4-piperidone and 3-chlorobenzyl chloride essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record: ord-cf152d035bd342a79b21f9fce5360b92
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06642231B2

Reaction notes

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