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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478491Generated: October 25, 2026

2-Chlorobenzyl chloride → 1-[(2-Chlorophenyl)methyl]piperidin-4-one

https://huagongshe.com/reaction/478491

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorobenzyl chlorideHCID 11906—
Reactant4-PiperidoneHCID 33721—
Product1-[(2-Chlorophenyl)methyl]piperidin-4-oneHCID 11959531—

Reaction Steps

1-(2-Chlorobenzyl)-4-piperidone is prepared from 4-piperidone and 2-chlorobenzyl chloride essentially as described above in Example 38, Scheme C, step a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642231B2
Source datasetuspto-grants-2003_11
ORD IDord-f31bdd11fb7c48a7bb4d4421e73bc64f
Source noteuspto-grants-2003_11