Hydroxyamine hydrochloride → 1-(3-Phenoxypropyl)-4-piperidone oxime

HRID 478498Notes

Reaction equation

[O:1]([CH2:8][CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][C:14](=O)[CH2:13][CH2:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:19][OH:20]>>[O:1]([CH2:8][CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][C:14](=[N:19][OH:20])[CH2:13][CH2:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 443297Hydroxyamine hydrochloride

HCID 180022221-(3-Phenoxypropyl)piperidin-4-one

Product 1

HCID 180022261-(3-Phenoxypropyl)-4-piperidone oxime

Procedure

1-(3-Phenoxypropyl)-4-piperidone oxime is prepared from 1-(3-phenoxypropyl)-4-piperidone and hydroxylamine hydrochloride essentially as described above in Example 38, Scheme C, step b.

Sources & evidence

ORD record: ord-178d5fb19fc149b281ada3d540390501
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06642231B2

Reaction notes

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