4-Piperidone → 1-(2-Phenylsulfinylethyl)-4-piperidone

HRID 478514Notes

Reaction equation

HRID 478514 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][S:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:12]>>[C:13]1([S:11]([CH2:10][CH2:9][N:1]2[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]2)=[O:12])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 337214-PiperidoneHCID 99293((2-Chloroethyl)sulphinyl)benzene

Product 1

HCID 180021551-(2-Phenylsulfinylethyl)-4-piperidone

Procedure

1-(2-Phenylsulfinylethyl)-4-piperidone is prepared from 4-piperidone and 1-chloro-2-phenylsulfinylethane essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record
ord-5281c6c21cb34f7db2467ec8ea0a6224
Source dataset
uspto-grants-2003_11
Patent number
US06642231B2

Reaction notes

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