3-Aminopyridine → 2-(Pyridin-3-ylamino)nicotinaldehyde

HRID 478725Notes

Reaction equation

Cl[C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[NH2:11][C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1>>[N:14]1[CH:15]=[CH:16][CH:17]=[C:12]([NH:11][C:2]2[N:10]=[CH:9][CH:8]=[CH:7][C:3]=2[CH:4]=[O:6])[CH:13]=1

Participants

Reactant 2

HCID 100093-Aminopyridine

HCID 762582-Chloronicotinic acid

Product 1

HCID 180026102-(Pyridin-3-ylamino)nicotinaldehyde

Procedure

The procedure of Synthetic Example 1 or partly modified processes thereof were repeated using 2-chloronicotinic acid and 3-aminopyridine to obtain 2-(pyridin-3-ylamino)nicotinaldehyde.

Sources & evidence

ORD record: ord-aa431cd0efc346188055835e996c644b
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06642250B2

Reaction notes

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