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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478729Generated: October 26, 2026

Triethyl phosphonoacetate → Ethyl isonicotinylacetate

https://huagongshe.com/reaction/478729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethyl phosphonoacetateHCID 13345—
Reactant4-PyridinecarboxaldehydeHCID 13389—
ProductEthyl isonicotinylacetateHCID 12229233—

Reaction Steps

The procedure of Synthetic Example 4 was repeated using isonicotinaldehyde and ethyl diethylphosphonoacetate to obtain ethyl 3-(pyridin-4-yl)propionate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642250B2
Source datasetuspto-grants-2003_11
ORD IDord-818c3ddabf1f436c8fa301eba4571d0e
Source noteuspto-grants-2003_11