HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenol → 4-Methoxy-2-(3'-(trifluoromethyl)benzyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenol | HCID 9015 | — |
| Reactant | 3-(Trifluoromethyl)benzyl chloride | HCID 69716 | — |
| Product | 4-Methoxy-2-(3'-(trifluoromethyl)benzyl)phenol | HCID 22325200 | — |
Reaction Steps
Alkylation of 4-methoxyphenol with 3-(trifluoromethyl)benzyl chloride according to the procedure described in J. Chem. Soc. 2431 (1958) gave 4-methoxy-2-(3′-(trifluoromethyl)benzyl)phenol. This material was converted to compound 67, mp 226.5-228° C., and compound 68, mp 188-190° C., byu the procedure similar to that in Example 18 method B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06642268B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-ff443a482f5e49f8952470973ab25671 |
| Source note | uspto-grants-2003_11 |