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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478909Generated: October 29, 2026

Epichlorohydrin → HCID 18002803, compound

https://huagongshe.com/reaction/478909

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEpichlorohydrinHCID 7835—
Reactant4-BenzylpiperidineHCID 31738—
ProductHCID 18002803HCID 18002803100%

Reaction Steps

Treatment of amine 6 with epichlorohydrin, following the procedure described in Example 12, Step 1, gave crude 1-chloro-3-(4-benzylpiperidin-1-yl)propan-2-ol (29.03 g, >100%) as a clear, colorless oil:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642256B2
Source datasetuspto-grants-2003_11
ORD IDord-586efa5b4bd345809dc6d1162bda5090
Source noteuspto-grants-2003_11