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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 478910Generated: October 30, 2026

HCID 18002803, compound → HCID 18002801, compound

https://huagongshe.com/reaction/478910

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18002803HCID 18002803—
ReactantPhthalimide potassium saltHCID 24194345—
ProductHCID 18002801HCID 1800280186%

Reaction Steps

Treatment of 1-chloro-3-(4-benzylpiperidin-1-yl)propan-2-ol with potassium phthalimide, following the procedure described in Example 12, Step 2, gave 2-[3-(4-benzylpiperidin-1-yl)-2-hydroxypropyl]isoindole-1,3-dione (32.44 g, 86%) as a white solid:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642256B2
Source datasetuspto-grants-2003_11
ORD IDord-1c6e39370e2446d89abbbce3be43b878
Source noteuspto-grants-2003_11