Imidazole → HCID 129689385, compound

HRID 478944Notes

Reaction equation

HRID 478944 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[H+].[B-:7]([F:11])([F:10])([F:9])[F:8]>ClCCl.C(OCC)C>[F:8][B-:7]([F:11])([F:10])[F:9].[NH+:1]1[CH:5]=[CH:4][NH:3][CH:2]=1

Participants

5

Reactant 2

HCID 795ImidazoleHCID 28118Tetrafluoroboric acid

Product 1

HCID 129689385HCID 129689385, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6344DichloromethaneSolvent2×

Procedure

To a solution of imidazole (20 mmol) in dichloromethane (30 mL) at 0° C. HBF4 (20 mmol, 3.8g of a diethyl etherate) in dichloromethane is added dropwise. The reaction mixture is diluted with diethyl ether (100 mL) to precipitate the title compound. It is then filtered, washed with ether and recrystallized from ether.

Workup

  1. customat 0° C
  2. customto precipitate the title compound
  3. filtrationIt is then filtered
  4. washwashed with ether
  5. customrecrystallized from ether

Sources & evidence

ORD record
ord-1296a4ff55a94f10909d5daab4022bdf
Source dataset
uspto-grants-2003_11
Patent number
US06642373B2

Reaction notes

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