2-Nitropropane → HCID 21951129, compound

Participants

Reaction Steps

To a solution of 450 g (7.40 moles) of ethanolamine in 1000 ml of isopropanol, 607.8 g (6.55 moles) of 2-nitropropane and 100 ml of water are added. The solution is stirred at room temperature and 225.4 g (7.5 moles) of paraformaldehyde and 7 ml of 20% aqueous solution of sodium hydroxide (% w/v) are added, under stirring and maintaining the temperature at room temperature for 16 hours. The mixture is then heated to 50° C. being nitrogen bubbled into the mixture to eliminate the formaldehyde in excess. The mixture is then used for the reaction, without any isolation of the product.

Provenance & Evidence