Epichlorohydrin → HCID 18003349, compound

HRID 478977Notes

Reaction equation

HRID 478977 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:9][C:8]([CH3:11])([CH3:10])[N:7]([CH3:12])[C:6]([CH3:14])([CH3:13])[C:5]1=[O:15].[CH2:16]([CH:18]1[O:20][CH2:19]1)Cl.[OH-].[Na+]>S([O-])(O)(=O)=O.C([N+](CCCC)(CCCC)CCCC)CCC.O>[CH3:13][C:6]1([CH3:14])[N:7]([CH3:12])[C:8]([CH3:10])([CH3:11])[CH2:9][N:4]([CH2:3][CH2:2][O:1][CH2:16][CH:18]2[CH2:19][O:20]2)[C:5]1=[O:15]

Participants

6

Reactant 3

HCID 7835EpichlorohydrinHCID 14798Sodium HydroxideHCID 22392274HCID 22392274, compound

Product 1

HCID 18003349HCID 18003349, compound

Reagents, catalysts & solvents 2

HCID 94433Tetrabutylammonium hydrogen sulfateCatalystHCID 962WaterSolvent

Procedure

Following the procedure described in Example 7, 80 g (0.37 moles) of 1-(2-hydroxyethyl)-3,3,4,5,5-pentamethyl-piperazin-2-one are reacted with 118 g (1.28 moles) of epichlorohydrin in the presence of 13 g (38 mmoles of tetrabutylammonium hydrogen sulfate and 16.4 g (0.41 moles) of sodiumhydroxide dissolved in 41 ml of water.

Sources & evidence

ORD record
ord-f69f1f2138ff423fa6aa282f036d3c68
Source dataset
uspto-grants-2003_11
Patent number
US06642383B2

Reaction notes

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