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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 479085Generated: November 3, 2026

Imidazole → HCID 11829501, compound

https://huagongshe.com/reaction/479085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantCyclopropanecarbonyl chlorideHCID 77637—
SolventTetrahydrofuranHCID 8028—
ProductHCID 11829501HCID 11829501102.1%

Reaction Conditions

Temperature0 °C

Reaction Steps

A solution of cyclopropanecarbonyl chloride (10.0 g) in dry tetrahydrofuran was added dropwise to a solution of imidazole (13.0 g, 2 equivalents) stirred at 0° C. After 1 hour the solid was filtered and the filtrate evaporated to give the title compound (13.3 g), NMR 1.2 (m, 2H), 1.38 (m, 2H), 2.21 (m, 1H), 7.12 (d, 1H), 7.55 (d, 1H), 8.34 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06642418B1
Source datasetuspto-grants-2003_11
ORD IDord-aeb4debf6a98429a89e093bb05b5679d
Source noteuspto-grants-2003_11