反应详情

Carvedilol (4 g) was dissolved in 39 mL pyridine by stirring at room temperature. 70 mL of water was then added dropwise until crystallization began. The solution was left at room temperature without stirring for about 80 h, then the crystals were filtered through a buchner and dried in a desiccator at room temperature (connected to air pump) until constant weight to yield Carvedilol Form III.

1. waitThe solution was left at room temperature
2. stirringwithout stirring for about 80 h
3. filtrationthe crystals were filtered through a buchner
4. customdried in a desiccator at room temperature (connected to air pump) until constant weight