HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Carvedilol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Carvedilol | HCID 2585 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Carvedilol | HCID 2585 | — |
| Product | 2-(2-Methoxyphenoxy)ethyl amine | HCID 1713005 | — |
Reaction Steps
Carvedilol (4 g) was dissolved in 39 mL pyridine by stirring at room temperature. 70 mL of water was then added dropwise until crystallization began. The solution was left at room temperature without stirring for about 80 h, then the crystals were filtered through a buchner and dried in a desiccator at room temperature (connected to air pump) until constant weight to yield Carvedilol Form III.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06699997B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-dff0d52934d545ca870762f931e3867d |
| Source note | uspto-grants-2004_03 |