反应详情

温度

55 °C

Carvedilol (4 g) was dissolved in 267 mL dioxane/water in the ratio 1:1.4 respectively by heating the mixture under stirring at 55° C. water bath. The resulting solution was left at room temperature without stirring for about 15 h then the crystals were filtered through a buchner funnel and dried in a desiccator (connected to air pump) until constant weight to yield Carvedilol Form III in a mixture with Carvedilol Form II.

1. temperatureby heating the mixture
2. waitThe resulting solution was left at room temperature
3. stirringwithout stirring for about 15 h
4. filtrationthe crystals were filtered through a buchner funnel
5. customdried in a desiccator (connected to air pump) until constant weight