HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47919Generated: October 27, 2026
Carvedilol → 2-(2-Methoxyphenoxy)ethyl amine
https://huagongshe.com/reaction/47919
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Carvedilol | HCID 2585 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | Carvedilol | HCID 2585 | — |
| Product | 2-(2-Methoxyphenoxy)ethyl amine | HCID 1713005 | 425.4% |
Reaction Steps
Carvedilol (40 g) was dissolved in 150 ml of ethanol and 40 ml water. The solution was heated with agitation to 60-70° C. until the solid material was completely dissolved. The solution is then cooled with agitation to 10° C. over a period of 3 hours. After stirring the suspension for an additional 2.75 hours, the product is filtered. Pure Carvedilol Form III (35 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06699997B2 |
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| Source dataset | uspto-grants-2004_03 |
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| ORD ID | ord-431055c90377481491f6767ab526eefc |
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| Source note | uspto-grants-2004_03 |
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