Hydrochloric Acid → HCID 18770379, compound

HRID 479400Notes

Reaction equation

HRID 479400 reaction equation
[ClH:1].[C:2]([C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[CH:14]=[CH:15]/[C:16]([N:18]2[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][CH2:26][N:27]3[CH2:32][CH2:31][N:30]([C:33](=[O:50])/[CH:34]=[CH:35]/[CH:36]=[CH:37]/[C:38]4[CH:43]=[CH:42][C:41]([C:44]([CH3:47])([CH3:46])[CH3:45])=[CH:40][C:39]=4[O:48][CH3:49])[CH2:29][CH2:28]3)[CH2:20][CH2:19]2)=[O:17])=[C:8]([O:51][CH3:52])[CH:7]=1)([CH3:5])([CH3:4])[CH3:3]>C(O)C>[ClH:1].[ClH:1].[C:2]([C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[CH:14]=[CH:15]/[C:16]([N:18]2[CH2:19][CH2:20][N:21]([CH2:24][CH2:25][CH2:26][N:27]3[CH2:32][CH2:31][N:30]([C:33](=[O:50])/[CH:34]=[CH:35]/[CH:36]=[CH:37]/[C:38]4[CH:43]=[CH:42][C:41]([C:44]([CH3:45])([CH3:47])[CH3:46])=[CH:40][C:39]=4[O:48][CH3:49])[CH2:29][CH2:28]3)[CH2:22][CH2:23]2)=[O:17])=[C:8]([O:51][CH3:52])[CH:7]=1)([CH3:3])([CH3:4])[CH3:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12988315HCID 12988315, compound

Product 1

HCID 18770379HCID 18770379, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Concentrated hydrochloric acid (0.025 ml; 0.30 mmol) was added to a solution of 1,3-bis[4-[(E,E)-5-(4-tert-butyl-2-methoxyphenyl)-2,4-pentadienoyl]-1-piperazinyl]propane (49 mg; 0.070 mmol) in ethanol (5 ml) and the reaction mixture was concentrated under reduced pressure. A process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure was performed twice to obtain the title compound as a pale yellow amorphous powder.

Workup

  1. concentrationthe reaction mixture was concentrated under reduced pressure
  2. concentrationA process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure

Sources & evidence

ORD record
ord-b221f5960c1e4284a98031c388362670
Source dataset
uspto-grants-2003_11
Patent number
US06645957B2

Reaction notes

Loading…