Hydrochloric Acid → HCID 86759250, compound

HRID 479430Notes

Reaction equation

HRID 479430 reaction equation
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([C:14]2[CH:57]=[CH:56][C:17]([C:18]([N:20]3[CH2:25][CH2:24][CH:23]([CH2:26][N:27](C)[CH2:28]C4CCN(C(=O)C5C=CC(C6C=C(OC)C(OC)=C(OC)C=6)=CC=5)CC4)[CH2:22][CH2:21]3)=[O:19])=[CH:16][CH:15]=2)[CH:7]=[C:8]([O:12][CH3:13])[C:9]=1[O:10][CH3:11]>C(O)C>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]([C:14]2[CH:57]=[CH:56][C:17]([C:18]([N:20]3[CH2:25][CH2:24][CH:23]([CH2:26][NH:27][CH3:28])[CH2:22][CH2:21]3)=[O:19])=[CH:16][CH:15]=2)[CH:7]=[C:8]([O:12][CH3:13])[C:9]=1[O:10][CH3:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18770412HCID 18770412, compound

Product 1

HCID 86759250HCID 86759250, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Concentrated hydrochloric acid (0.045 ml; 0.54 mmol) was added to a solution of N,N-bis[[1-[4-(3,4,5-trimethoxyphenyl)benzoyl]-4-piperidinyl]methyl]methylamine (142 mg; 0.18 mmol) in ethanol (5 ml) and the reaction mixture was concentrated under reduced pressure. A process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure was performed twice to obtain the title compound as a colorless amorphous powder.

Workup

  1. concentrationthe reaction mixture was concentrated under reduced pressure
  2. concentrationA process of adding ethanol (10 ml) to the residue and concentrating the mixture under reduced pressure

Sources & evidence

ORD record
ord-6b735bf562c547ec8f5158a910bf6692
Source dataset
uspto-grants-2003_11
Patent number
US06645957B2

Reaction notes

Loading…