p-Toluenesulfonic acid → HCID 18770579, compound

HRID 479509Notes

Reaction equation

HRID 479509 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[N:2]1.[Cl:10][C:11]1[CH:19]=[CH:18][C:14]([C:15]([NH2:17])=[O:16])=[CH:13][CH:12]=1.[CH:20]1([CH:26]=O)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:1]1([CH:26]([CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[NH:17][C:15](=[O:16])[C:14]2[CH:18]=[CH:19][C:11]([Cl:10])=[CH:12][CH:13]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[N:2]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 120844-ChlorobenzamideHCID 16275CyclohexanecarboxaldehydeHCID 178418385HCID 178418385, compound

Product 1

HCID 18770579HCID 18770579, compound

Procedure

Benzotriazole, 4-chlorobenzamide, cyclohexanecarboxaldehyde, and p-toluenesulfonic acid were processed as in Example 53A to provide the desired product.

Sources & evidence

ORD record
ord-6301c16bac224a749aaa53de912ee631
Source dataset
uspto-grants-2003_11
Patent number
US06645968B2

Reaction notes

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