HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nicotinamide → N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nicotinamide | HCID 936 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 2,2-Dichloropropanal | HCID 10975496 | — |
| Reactant | HCID 178418385 | HCID 178418385 | — |
| Product | N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]nicotinamide | HCID 18770600 | — |
Reaction Steps
A suspension of nicotinamide, 2,2-dichloropropionaldehyde, benzotriazole, and p-toluenesulfonic acid was processed as described in Example 53A to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06645968B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-f750b20da4414c5e98be51106d5df771 |
| Source note | uspto-grants-2003_11 |