HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl piperidine-2-carboxylate → Ethyl 1-[(6-bromopyridin-2-yl)methyl]-piperidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl piperidine-2-carboxylate | HCID 27517 | — |
| Reactant | 6-Bromopyridine-2-carbaldehyde | HCID 2757009 | — |
| Product | Ethyl 1-[(6-bromopyridin-2-yl)methyl]-piperidine-2-carboxylate | HCID 18771756 | — |
Reaction Steps
13] Ethyl (2-piperidyl)carboxylate (0.92 mL, 5.92 mmol) was added to a solution of 6-bromo-2-pyridinecarboxaldehyde (1.0 g, 5.38 mmol) to give ethyl 1-[(6-bromopyridin-2-yl)methyl]-piperidine-2-carboxylate as a colorless oil). MS m/z: 327.1 (M+H). Calc'd for C14H1gBrN2O2—327.22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06645990B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-8be46c9b314c47b385c043a37598c252 |
| Source note | uspto-grants-2003_11 |