Potassium Iodide → HCID 11333911, compound

HRID 479894Notes

Reaction equation

HRID 479894 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[CH:7]=[CH:6][C:5]=1[OH:13].Cl[CH2:15][C:16]([NH2:18])=[O:17].C(=O)([O-])[O-].[Ca+2].[I-].[K+]>O.CC(C)=O>[CH3:1][O:2][CH2:3][C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[CH:7]=[CH:6][C:5]=1[O:13][CH2:15][C:16]([NH2:18])=[O:17]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 6580ChloroacetamideHCID 10112Calcium CarbonateHCID 113558782-(Methoxymethyl)-4-nitrophenol

Product 1

HCID 11333911HCID 11333911, compoundYield 61%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

25 g of 2-methoxymethyl-4-nitrophenol, 14 g of chloroacetamide, 18.9 g of calcium carbonate, and 12.5 g of potassium iodide in a 150 ml of acetone are heated under reflux for four hours. Subsequently the reaction mixture is cooled to room temperature and poured into water. The resulting precipitate is filtered, washed with water and subsequently dried. 20 g of a pale yellow product is obtained having a melting point of from 157 to 158° C.

Workup

  1. temperatureunder reflux for four hours
  2. filtrationThe resulting precipitate is filtered
  3. washwashed with water
  4. customsubsequently dried

Sources & evidence

ORD record
ord-cc3c17d72ab74fb2859dcee1f2813a9c
Source dataset
uspto-grants-2003_11
Patent number
US06648923B1

Reaction notes

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