HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminobenzoic Acid → 4-Anilino-5-bromo-2-(3-carboxyanilino)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminobenzoic Acid | HCID 7419 | — |
| Reactant | 5-bromo-2-chloro-N-phenylpyrimidin-4-amine | HCID 11403389 | — |
| Product | 4-Anilino-5-bromo-2-(3-carboxyanilino)pyrimidine | HCID 18768036 | — |
Reaction Steps
Using an analogous method to that described in Method 1, but starting from 4-anilino-5-bromo-2-chloropyrimidine and 3-aminobenzoic acid, the product was obtained. NMR: 7.2-7.4 (m, 4H), 7.55-7.6 (m, 3H), 7.8 (dd, 1H), 7.95 (s, 1H), 8.4 (s, 1H), 9.3 (br s, 1H), 10.2 (br s 1H); MS (MH+): 385, 387.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06649608B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-de4b2118f3ce4bea94c85482f633f8ad |
| Source note | uspto-grants-2003_11 |