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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 480039Generated: October 29, 2026

Trifluoroacetic acid → HCID 18768675, compound

https://huagongshe.com/reaction/480039

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantChlorineHCID 24526—
ReactantHCID 17887098HCID 17887098—
ProductHCID 18768675HCID 18768675—

Reaction Conditions

Temperature40 °C

Reaction Steps

A solution containing 1.7 g (0.0046 mole) of the product of example 33, 15 ml of CF3COOH and 15 ml of CH2 Cl2 is heated at 40° C. for 3 hours. The solvent is evaporated off under vacuum, concentrated ammonia is added, and then an extraction with ethyl acetate carried out. The solvent is evaporated off and the named product obtained: M. P. 193-195° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06649627B1
Source datasetuspto-grants-2003_11
ORD IDord-c09d25d9db654d42ad334327ecc3ee63
Source noteuspto-grants-2003_11