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HRID480039

反应详情

EQUATION

反应方程式

HRID 480039 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：ClCl
HCID24526

Chlorine

Cl2

结构：COC(=O)c1ccc(CN2CCC(CNC(=O)OC(C)(C)C)CC2)nc1
HCID17887098

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(CN2CCC(CN)CC2)nc1.O=C(O)C(F)(F)F
HCID18768675

未命名化合物

CONDITIONS

反应条件

温度
40 °C

PROCEDURE

实验过程

A solution containing 1.7 g (0.0046 mole) of the product of example 33, 15 ml of CF3COOH and 15 ml of CH2 Cl2 is heated at 40° C. for 3 hours. The solvent is evaporated off under vacuum, concentrated ammonia is added, and then an extraction with ethyl acetate carried out. The solvent is evaporated off and the named product obtained: M. P. 193-195° C.

WORKUP

后处理

  1. customThe solvent is evaporated off under vacuum, concentrated ammonia
  2. additionis added
  3. extractionan extraction with ethyl acetate
  4. customThe solvent is evaporated off
  5. customthe named product obtained