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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 480239Generated: October 28, 2026

HCID 20601577, compound → HCID 18768964, compound

https://huagongshe.com/reaction/480239

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 20601577HCID 20601577—
ReactantAmmonia methanolHCID 21705897—
ProductHCID 18768964HCID 1876896450%

Reaction Steps

To 2-(2-cyclohexylmethyl-4-morpholin-4-yl-4-oxo-butyrylamino)-4-piperidin-1-yl-butyric acid benzyl ester (0.10 g, 0.18 mmol) was added NH3/MeOH (2.0 M, 10 mL) in a sealed tube and the mixture was stirred at room temperature for 3 days. The solvent was evaporated to give the title compound in 50% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06649642B2
Source datasetuspto-grants-2003_11
ORD IDord-fdcf872366f745e6a5e6044552ac6cbe
Source noteuspto-grants-2003_11