HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20601577, compound → HCID 18768964, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20601577 | HCID 20601577 | — |
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Product | HCID 18768964 | HCID 18768964 | 50% |
Reaction Steps
To 2-(2-cyclohexylmethyl-4-morpholin-4-yl-4-oxo-butyrylamino)-4-piperidin-1-yl-butyric acid benzyl ester (0.10 g, 0.18 mmol) was added NH3/MeOH (2.0 M, 10 mL) in a sealed tube and the mixture was stirred at room temperature for 3 days. The solvent was evaporated to give the title compound in 50% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06649642B2 |
| Source dataset | uspto-grants-2003_11 |
| ORD ID | ord-fdcf872366f745e6a5e6044552ac6cbe |
| Source note | uspto-grants-2003_11 |